Driving Automation, Efficiency, and Standardization in Clinical Research

At Clymb Clinical, we’re passionate about making clinical research more efficient, automated, and standardized. That’s why we’ve collaborated with CDISC to launch the first ARS-compliant packages in the eTFL Portal—a game-changing step in modernizing how analysis results are managed and shared.

The Impact of Our Collaboration

Clinical trials generate massive amounts of data, but the way we report and analyze results hasn’t changed much over the years. Tables, figures, and listings (TFLs) are often static, time-consuming to create, and hard to reuse. The Analysis Results Standard (ARS)—released by CDISC in April 2024—was designed to change that by introducing a structured, machine-readable framework that improves automation and traceability. However, implementing ARS can be complex. That’s where the eTFL Portal comes in. By working with CDISC, Clymb Clinical has helped develop the first set of ARS-compliant packages, making it easier for the industry to adopt standardized, reusable, and automated analysis results.

What is the eTFL Portal?

Think of the eTFL Portal as a library of ready-to-use analysis templates that follow CDISC standards. It provides:

• Pre-built ARS-compliant examples – Covering key safety analysis topics like demographics, adverse events, and lab results.
• Standardized metadata – Ensuring analysis data aligns with ADaM and ARS models for better consistency.
• Machine-readable datasets – Helping automate regulatory submissions, reports, and publications.
• Seamless integration with CDISC standards – Supporting SDTM, CDASH, and future automation tools.

With these resources, researchers, CROs, and sponsors can save time, reduce errors, and ensure regulatory compliance—without reinventing the wheel.

What’s Next for ARS and the eTFL Portal?

The launch of the first ARS-compliant packages is just the beginning. The eTFL Portal will continue to evolve, expanding to include:

• More analysis templates, including efficacy and therapeutic area-specific examples.
• Better integration with metadata-driven automation tools.
• More advanced automation features to further simplify analysis result generation.

At Clymb Clinical, we’re excited to be at the forefront of this transformation, ensuring that clinical trial data is faster, smarter, and more reliable than ever before.

How Clymb Clinical is Leading the Way

At Clymb Clinical, we specialize in metadata-driven automation, and our role in developing the eTFL Portal reflects our expertise in clinical data standardization. Our contributions focus on:

• Making ARS metadata system-agnostic, so it can be used across different platforms.
• Enabling "create once, use many times" analysis results, improving efficiency across multiple studies.
• Embedding automation throughout the process, from dataset creation to regulatory submission.

This collaboration is a major step toward a future where clinical data is standardized, automated, and easier to manage.

See how Clymb Clinical and CDISC are making ARS implementation easier and more effective.

Visit the eTFL Portal

by Clymb Clinical

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